While others target the symptoms, we target the source.


Bacterial dysbiosis can be common in patients with IBS.


Microbiome dysbiosis can impair normal gut metabolism.


Abnormal gut metabolism disrupts gut barrier function and can exacerbate symptoms of IBS.

Epithelial cell damage

Epithelial cell damage

Leaky gut

Leaky gut


The glycans in Holigos® IBS Restore act as selective prebiotics to help rebalance the gut microbiome and increase production of beneficial metabolites. Holigos® IBS Restore is a medical food for the dietary management of IBS.


The glycans in Holigos® IBS Restore improve gut barrier integrity and gut motility.

Balance restored

Balance restored

Healthy epithelial cells

Healthy epithelial cells

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Safety & Tolerability

A double-blinded, placebo-controlled trial demonstrated:

Frequently Asked Questions

Yes! We know that people often like to try before they buy, so we’ve supplied many health care providers with full 28-stick sample boxes to give to their patients. If you would like a sample, please ask your healthcare provider.
Human milk oligosaccharides (HMOs) are a type of complex carbohydrate found in breast milk. They’re known as natural digestive nutrients because of their prebiotic properties. Prebiotics work with your body’s own good bacteria, unlike probiotics which add foreign bacteria to your body. So simply put, HMOs work by selectively nourishing and stimulating the growth of your own good gut bacteria, activating them to thrive and outperform bad bacteria.

Holigos® is a soluble powder that you can easily mix with any food or beverage, warm or cold — so do what works best for you, like adding it to your breakfast or favorite drink.

Holigos® is odor free and has little to no taste (slightly sweet if mixed in water).

Take a look at our Instagram page to find recipes and fun “mixtures” to incorporate Holigos® into your daily routine!

Our focus is health and safety, so we presented our scientific-based conclusion that the ingredients found in Holigos® are safe to both the US Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA). Both agencies, independently, have reviewed the ingredients in Holigos® and have accepted them as safe. Additionally, in clinical studies, hundreds of babies and adults have consumed our human milk oligosaccharides, even at higher doses than the daily dose found in Holigos®. No issues with safety and no severe side effects have been reported.

Since we make real changes in your gut microbiome, it is not unusual to experience some mild side effects when you start taking Holigos®.

Research shows that over 96% of people who participated in our clinical study found Holigos® to be tolerable. The most common temporary side effects were mild gastrointestinal (GI) symptoms such as abdominal pain, gas, and bloating. These are perfectly normal and actually an indication that your microbiome is beginning to improve.

These sensations tend to disappear without any intervention after a few days, though for some people it may take slightly longer for their system to settle. While it might feel a little unpleasant during these first days, know that these are signs that your microbiome is changing to help you reclaim control of your digestive health, so it’s worth sticking with it.

If you are still experiencing these symptoms after the first few weeks but they are manageable, it is perfectly safe to continue with the products. Your gut will find a new balance by itself within the first month or two.

If, however, you experience any more serious side effects, such as nausea or increased IBS symptoms, you should stop taking the product and seek advice from your doctor.

We do not believe that Holigos® meets the strict definition of vegan.

Holigos® has been formulated for adults and children 12 years of age and older. Note: In the event a healthcare provider recommends Holigos® to a child under the age of 12, the dosage should be as directed by the healthcare provider.

Safe and Well-Tolerated

Safe and Well-Tolerated

Holigos® IBS Restore is a medical food available as a once-daily dose.

Holigos® IBS Restore ingredients were reviewed and a no questions asked letter was issued by the FDA.

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