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Diet is a core element in the pathogenesis of IBS

The pathogenesis of IBS is exceedingly complex and multi-factorial, but diet plays a key role. The gut microbiota is recognized as a key factor in the pathogenesis of IBS2 and diet is a major determinant of the gut microbiota3. Also, about two thirds of patients develop symptoms soon eating a meal, especially foods rich in fats4 and certain carbohydrates5, especially FODMAPs6. Therefore, diet is both a trigger of symptoms and a core element of IBS pathogenesis.

Medical nutrition is specifically tailored for the patient's distinct nutritional needs and addresses dietary causes

Medical nutrition involves managing a patient using specifically-tailored, nutritional interventions under the guidance of medical professional. It is much more than taking supplements or probiotics. This can be done using guidelines for first-line, dietary management of IBS, for example the NICE guidelines7. An alternative is to use medical foods. Medical nutrition works; a recent survey8 of 1500 US gastroenterologists found that 90% of respondents believed dietary management was at least as good or better than existing pharmacologic therapies for IBS.

Holigos™ IBS is a medical food specifically formulated to address the specific nutritional needs of IBS patients and restore gut homeostasis

Medical foods are a specific class of food product defined in the Orphan Drug Act of 1988 [21 USC 360ee (b)(3)]. They are specifically formulated for the dietary management of a defined disease or condition for which there are distinctive nutritional requirements. Holigos™ IBS is formulated to modulate the gut microbiota of all sub-types of IBS patient to increase the activity of beneficial bacteria and increase nutrients and metabolites such as SCFAs.

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