Holigos® IBS Restore

Clinically shown IBS symptom relief within 4 weeks.†

Holigos® IBS Restore is a medical food formulated for daily and proactive dietary management of IBS.


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Holigos® IBS Restore is a targeted microbiome nutrient clinically shown to help relieve pain, bloating, constipation, and/or diarrhea due to IBS.†

Holigos® IBS Restore is an odorless, tasteless powder. Take it once a day, mixed with hot or cold food or drink. Use as directed under medical supervision.

Holigos® IBS Restore includes two bioactive prebiotics, a proprietary blend of two HMOs

  • 2'-Fucosyllactose
  • Lacto-N-neotetraose

Does Not Contain

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  • gluten-free-icon


  • sugar-free-icon


  • added-flavors-icon


  • artificial-dyes-icon


  • active-yeast-icon


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Clinically-shown IBS symptom relief

Holigos® IBS Restore is a medical food formulated for daily and proactive dietary management of IBS. It has been clinically shown to help provide relief for all subtypes of IBS including IBS-C (constipation), IBS-D (diarrhea), and IBS-M (constipation and diarrhea).

Clinical Results

In a 12-week trial Holigos® demonstrated multiple benefits.

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Frequently Asked Questions

Human milk oligosaccharides (HMOs) are a type of complex carbohydrate found in breast milk. They’re known as natural digestive nutrients because of their prebiotic properties. Prebiotics work with your body’s own good bacteria, unlike probiotics which add foreign bacteria to your body. So simply put, HMOs work by selectively nourishing and stimulating the growth of your own good gut bacteria, activating them to thrive and outperform bad bacteria.

Since we make real changes in your gut microbiome, it is not unusual to experience some mild side effects when you start taking Holigos®.

The most common temporary side effect is mild gastrointestinal (GI) symptoms such as abdominal pain, gas, and bloating. These are perfectly normal and actually an indication that your microbiome is beginning to improve.

These sensations tend to disappear without any intervention after a few days, though for some people it may take slightly longer for their system to settle. While it might feel a little unpleasant during these first days, know that these are signs that your microbiome is changing to help you reclaim control of your digestive health, so it’s worth sticking with it.

If you are still experiencing these symptoms after the first few weeks but they are manageable, it is perfectly safe to continue with the products. Your gut will find a new balance by itself within the first month or two.

If, however, you experience any more serious side effects, such as nausea or increased IBS symptoms, you should stop taking the product and seek advice from your doctor.

Holigos® IBS Restore is a medical food and should be taken under the supervision of a doctor.

It is formulated to help relieve the severity and frequency of IBS symptoms in adults (12 and older). Holigos® IBS Restore may be used by all IBS subtypes including IBS-M, IBS-C and IBS-D patients.

In our clinical study, patients reported significant benefits in 4 weeks. Participants have told us that they start seeing changes after 1-2 weeks. Everyone is different, so it may take your gut microbiome a little longer to rebalance.